HKU Researchers Develop Nasal Spray for Pre-Hospital Stroke Treatment
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Researchers at the University of Hong Kong have developed a pioneering nasal spray that delivers neuroprotective drugs directly to the brain to treat ischemic strokes before patients reach a hospital.
The nano dry-powder spray, created in collaboration with the Advanced Biomedical Instrumentation Centre (ABIC), bypasses the blood-brain barrier to rapidly minimize brain tissue death and subsequent neurological damage.
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- HKU researchers developed nano dry-powder nasal spray bypassing blood-brain barrier for ischemic strokes (84% of cases).
- In animal models, <30-min administration reduced brain necrosis >80%, protected functions, cut inflammation.
- Emergency pre-hospital aid; advancing to toxicology, trials for home use like inhaler.
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